Iris Jonkers is assistant professor at the Department of Genetics, University Medical Center Groningen, the Netherlands. Her focus is to comprehend how genetic variation associated with celiac disease changes gene expression networks and subsequent disease-associated phenotypes. Her background is in molecular biology, specializing in the basic mechanism of transcription regulation. She did her PhD in the group of prof. Joost Gribnau (ErasmusMC, Rotterdam, the Netherlands) on X chromosome inactivation and her postdoctoral training in the group of prof. John T Lis (Cornell University, New York, USA), on the subject of transcription elongation. After this, she wanted to apply her basic understanding of transcription regulation to the understanding of autoimmune diseases, specifically celiac disease. Now, she and her team work to understand how genetic variants disrupt immune related processes in celiac disease by combining innovative molecular technologies, large data sets and disease-specific samples. Her work is supported by a Rosalind Franklin Fellowship and an NWO-Vidi personal grant.